Usefulness of cardiovascular magnetic resonance imaging for the evaluation of valve opening and closing kinetics in aortic stenosis

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dc.contributor.authorGarcia, Julio-
dc.contributor.authorPibarot, Philippe-
dc.contributor.authorCapoulade, Romain-
dc.contributor.authorLe Ven, Florent-
dc.contributor.authorKadem, Lyes-
dc.contributor.authorLarose, Éric-
dc.description.abstractAims : The aims of this study were : (i) to determine the feasibility and reproducibility of the measurement of valve kinetic parameters by cardiovascular magnetic resonance (CMR) and (ii) to examine the association between these parameters and markers of a poor prognosis in patients with aortic stenosis (AS). Methods and results : Eight healthy control subjects and 71 patients with AS (0.60 cm2 = EOA = 1.90 cm2) underwent transthoracic echocardiography (TTE) and CMR. The valve opening slope (OS) and closing slope (CS) were calculated from instantaneous effective orifice area (EOA) curves obtained by CMR. Intra- and inter-observer variability were 4.8 ± 3.9 and 5.0 ± 4.1%, respectively, for OS, 3.8 ± 2.9 and 4.0 ± 3.1% for CS. OS was significantly related to the plasma level of NT-pro-brain natriuretic peptide (BNP) (r = -0.36, P = 0.002), whereas the EOA or gradient were not. Conclusion : This study demonstrates the excellent feasibility and reproducibility of CMR for the measurement of valve kinetic parameters in patients with AS. Larger studies are needed to confirm the incremental prognostic value of these new CMR parameters of aortic valve kinetics in patients with severe AS.fr_CA
dc.publisherOxford University Pressfr_CA
dc.subjectAortic stenosisfr_CA
dc.subjectCardiovascular magnetic resonancefr_CA
dc.subjectAortic valvefr_CA
dc.subjectValve kineticsfr_CA
dc.titleUsefulness of cardiovascular magnetic resonance imaging for the evaluation of valve opening and closing kinetics in aortic stenosisfr_CA
dc.typeCOAR1_1::Texte::Périodique::Revue::Contribution à un journal::Article::Article de recherche-
dcterms.bibliographicCitationEuropean Heart Journal. Cardiovascular Imaging, Vol. 14 (8), 819–826 (2013)fr_CA
dc.audienceProfesseurs (Enseignement supérieur)fr_CA
dc.subject.rvmAorte -- Rétrécissementfr_CA
dc.subject.rvmAppareil cardiovasculaire -- Imagerie par résonance magnétiquefr_CA
dc.subject.rvmValvule semi-lunaire de l'ostium aortiquefr_CA
rioxxterms.versionVersion of Recordfr_CA
rioxxterms.projectgrant # 343165-07fr_CA
rioxxterms.project.funder_nameNatural Sciences and Engineering Research Council of Canadafr_CA
Collection:Articles publiés dans des revues avec comité de lecture

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