La prévalence de la carence en fer, de l'anémie et leurs déterminants chez les adultes Inuit du Nunavik, Québec
|Advisor:||Ayotte, Pierre; Lemire, Mélanie|
|Abstract:||Context: Inuit are disproportionately affected by iron deficiency (ID) and anemia compared to the general Canadian population. Both conditions can negatively affect cognitive and immune system functioning, physical performance, and quality of life. ID, nutritional deficiencies, and inflammation can all cause anemia. Distal causes, including social determinants of health, may also contribute to anemia and ID. Objective: To assess the prevalence of ID and anemia and to study their major proximal and distal risk and protective factors in Nunavimmiut. Methods: We used data from the Qanuilirpitaa? 2017 Nunavik Inuit Health Survey obtained from blood analyses, questionnaires, and medical records of Inuit adults 16 years of age and older. Descriptive analyses were conducted to present the prevalence of ID and anemia. Subsequently, bivariate, and multivariate analyses were performed to study their proximal and distal risk and protective factors. Results: Prevalence of ID (18%) and anemia (19%) among Nunavimmiut in 2017 were similar to those of Inuit elsewhere in Canada, but higher than those of the general Canadian population. Among Nunavimmiut women, prevalence of ID and anemia have decreased significantly since the 2004 Qanuippitaa? Survey. In 2017, the prevalence of ID was highest among women of childbearing age (33%) and that of anemia was highest among adults aged 50 years and older (31%). Several nutrients found in the traditional Inuit diet (vitamin D, selenium, omega 3) were positively associated with serum ferritin (SF) in women of childbearing age. In young adults (16 to 49 years old), positive serology for Helicobacter pylori was negatively associated with SF and hemoglobin. In adults 50 years of age and older, food insecurity was negatively associated with SF. Conclusion: The results of this project show the complexity of the etiology of ID and anemia in different sex and age groups in Nunavik and highlight the importance of implementing targeted interventions for each of these groups. The elevated prevalence of anemia in women of childbearing age and adults 50 years of age and older deserves a special attention as it represents a moderate public health problem according to the criteria of the World Health Organization. Keywords: Anemia, Iron deficiency, Hemoglobin, Ferritin, Inuit, Nunavik|
|Document Type:||Mémoire de maîtrise|
|Open Access Date:||2 May 2022|
|Collection:||Thèses et mémoires|
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