Utilisation du L-PRF conjointement à la thérapie initiale dans le traitement de la parodontite modérée à sévère : une étude randomisée contrôlée à double aveugle

Authors: Côté, Olivier
Advisor: Gonçalves, Reginaldo Bruno
Abstract: Periodontal disease is an inflammatory process characterized by the destruction of the supporting tissues of the teeth. To treat this disease, scaling and root planing are commonly used. The goal of this treatment is to eliminate inflammation by removing infected bacterial biofilm, calculus, infected cementum and dentin while debriding rough root surfaces to promote new periodontal attachment. This type of healing is expected to result in diminishing gingival inflammation causing decreased pocket depth, increased recession and clinical attachment gain. In order to maximize the cure from this therapy, several adjuvants have been used in the past. In this master's project, we will focus on the use of "leucocyte and platelet rich fibrin" (L-PRF) as an additive to initial therapy in order to improve its outcome. In order to validate this hypothesis, a double-blind, randomized, split-mouth type study was used to verify the problem. 8 healthy, non-smoking subjects with periodontitis will receive a scaling and root planing treatment with and without L-PRF applied inside the periodontal pocket. Subsequently, the subjects were followed for 8-13 months at the periodontics post-graduate clinic of Laval University in order to assess pocket depth, gingival recession as well as the level of clinical attachment of the treated teeth. The comparative results between the two treatments obtained under the conditions of our study demonstrate that there is no difference, regardless of the treatment modality chosen in terms of pocket depth reduction, recession or level of clinical attachment. In conclusion, both treatment options offer an adequate clinical alternative. On the other hand, it would be possible that L-PRF provides a benefit that was not evaluated in this study.
Document Type: Mémoire de maîtrise
Issue Date: 2021
Open Access Date: 20 September 2021
Permalink: http://hdl.handle.net/20.500.11794/70391
Grantor: Université Laval
Collection:Thèses et mémoires

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