Influence des maladies et conditions osseuses sur le succès implantaire : une revue systématique et méta-analyse

Authors: Mouradian, Nancy
Advisor: Chandad, Fatiha
Abstract: Dental implants are now widely used to replace missing teeth in partially or fully edentulous patients. Several risk factors associated to peri-implant diseases are now recognized such as poor oral health or smoking habits. However there is no consensus on several systemic factors that may interfere with gaining or maintaining osteointegration. The objective of this study was to systematically review the survival of implants and radiographic marginal bone loss around those implants in patients that have bone diseases or conditions that affect bone metabolism. A literature search of different databases was conducted for studies published between January 1990 and December 2019. The systematic review and meta-analysis were done according to the guidelines recommended by the "Preferred Reporting Items for Systematic Review and Meta-Analyses statement". Following the established inclusion and exclusion criteria, we selected six published articles on diabetic patients with 661 implants in total and two published studies on osteoporotic patients with 274 implants in total. In the diabetic population, peri-implant parameters were generally worse particularly when their diabetes was not controlled. Four of the studies were included in the meta-analysis. There was less bone loss in the non-diabetic population (mean difference 0.46 mm; 95% confidence interval (0.06-0.86), z=2.28, p=0.02) as compared to patients that have poorly controlled diabetes. There was no difference in implant survival rates in the two studied populations. As for osteoporotic patients there was no difference in implant survival or marginal bone loss when compared to healthy patients. This systematic review and meta-analysis showed that uncontrolled diabetic patients need to be treated with caution. No conclusions were drawn on any other bone diseases and conditions. More long-term studies are needed to establish guidelines to provide better patient care in the presence of systemic disease.
Document Type: Mémoire de maîtrise
Issue Date: 2021
Open Access Date: 14 June 2021
Grantor: Université Laval
Collection:Thèses et mémoires

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