Évolution du fardeau de la sténose aortique dans la province de Québec entre 2000 et 2015

Authors: Frieden, Philipp
Advisor: Clavel, Marie-Annick; Blais, Claudia
Abstract: Aortic stenosis is the third most common cardiovascular disease in high income countries after arterial hypertension and coronary artery disease and is the valvular disease that requires the most interventions. The prevalence of aortic stenosis has been shown to increase with age and is becoming a major public health concern. However, data on the epidemiological burden of AS are contradictory, with some studies reporting an increase in incidence and others rather suggesting a decrease. The treatment of aortic stenosis faces a major paradigm shift with the introduction of percutaneous aortic valve implantation. The introduction of this procedure has changed the management of patients who were previously inoperable or at high surgical risk. The burden of aortic stenosis in the province can therefore be influenced both by demographic factors and by changes in aortic stenosis management. Faced with the heterogeneity of the evolution of the burden of aortic stenosis elsewhere in the world and the change in the management of the disease in recent years, it is imperative to assess the evolution of the burden of aortic stenosis in the province of Quebec. The main hypothesis of the study is that, because of the increasing prevalence of cardiometabolic risk factors in high-income countries and the aging of the province's population, the burden of aortic stenosis has increased in the province of Quebec between the fiscal years 2000-2001 and 2015-2016. The main objective of the study is therefore to examine the evolution of the prevalence, incidence, all-cause mortality and use of aortic valve interventions in the province of Quebec from the fiscal years 2000-2001 to 2015-2016.
Document Type: Mémoire de maîtrise
Issue Date: 2021
Open Access Date: 8 February 2021
Permalink: http://hdl.handle.net/20.500.11794/68082
Grantor: Université Laval
Collection:Thèses et mémoires

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