Effet du statut socio-économique sur la rigidité artérielle et contribution des contraintes psychosociales au travail dans une cohorte de 9 000 travailleurs

Authors: Laberge Sévigny, Marylie
Advisor: Trudel, XavierBrisson, Chantal
Abstract: Objectives: Asses the effect of socio-economic status (SES) on arterial stiffness (AS). The achievement of this main objective is possible through the implementation of the following specific objectives: A. Measure the association between SES and AS B. Measure the contribution of job strain as an intermediate variable to explain the association between SES and AS. Methods: The design study is a prospective 24-year cohort study of 9 188 workers in Quebec City. The data collection was done in two times: at baseline (1991-1993) and at the end of follow-up, 24 years later (2015- 2018). SES was measured according to its three main indicators: education, total household income and occupation. Job strain was defined according to the Karasek’s model (demand-latitude) and measured with 18 items of the self-administered Job Content Questionnaire. AS was measured by the carotid-femoral pulse wave 24 years later, according to the golden standard. Differences in means were modelled, using analysis of covariance models. Results: Among women, low income was the only SES indicator that was associated with lower AS. After adjusting for socio-demographic factors, women with incomes of50,000 and more have an arterial stiffness average of 7.78 m/s (95% CI: 7.66-7.90) and those with incomes of49,999 and less have an average arterial stiffness of 0.28 m/s (95% CI: 0.10-0.46). After adjusting for lifestyle factors, this difference was 0.27 m/s (95% CI: 0.08-0.45). After adjusting for clinical factors, this average difference was 0.25 m/s (95% CI: 0.07-0.44). The income effect does not appear to be explained by exposure to CPS at work because adjusting for job strain yielded identical estimates. Conclusion: Income is an indicator of SES related to the dimension of material living conditions that explains the influence of social determinants on health. This may explain why only income seems to have an effect on the development of AS. It seems essential to aim for a better understanding of social inequalities in health and the underlying dynamics in order to enable the development and implementation of intervention measures for a more egalitarian distribution of resources.
Document Type: Mémoire de maîtrise
Issue Date: 2021
Open Access Date: 8 February 2021
Permalink: http://hdl.handle.net/20.500.11794/68071
Grantor: Université Laval
Collection:Thèses et mémoires

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