Prosthesis-patient mismatch : an update

Authors: Dumesnil, Jean G.Pibarot, Philippe
Abstract: Prosthesis-patient mismatch (PPM) is present when the effective orifice area of the inserted prosthetic valve is too small in relation to body size. Its main hemodynamic consequence is to generate higher than expected gradients through normally functioning prosthetic valves. The purpose of this review is to present an update on the present state of knowledge with regard to diagnosis, prognosis, and prevention of PPM. PPM is a frequent occurrence (20% to 70% of aortic valve replacements) that has been shown to be associated with worse hemodynam- ics, less regression of left ventricular hypertrophy, more cardiac events, and lower survival. Moreover, as opposed to most other risk factors, PPM can largely be prevented by using a prospective strategy at the time of operation.
Document Type: Article de recherche
Issue Date: 25 February 2011
Open Access Date: Restricted access
Document version: VoR
This document was published in: Current Cardiology Reports, Vol. 13 (3), 250–257 (2011)
Current Science
Alternative version: 10.1007/s11886-011-0172-7
Collection:Articles publiés dans des revues avec comité de lecture

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