Prosthetic heart valves : selection of the optimal prosthesis and long-term management

Authors: Pibarot, PhilippeDumesnil, Jean G.
Abstract: The introduction of valve replacement surgery in the early 1960s has dramatically improved the outcome of patients with valvular heart disease. Approximately 90 000 valve substitutes are now implanted in the United States and 280 000 worldwide each year; approximately half are mechanical valves and half are bioprosthetic valves. Despite the marked improvements in prosthetic valve design and surgical procedures over the past decades, valve replacement does not provide a definitive cure to the patient. Instead, native valve disease is traded for “prosthetic valve disease,” and the outcome of patients undergoing valve replacement is affected by prosthetic valve hemodynamics, durability, and thrombogenicity. Nonetheless, many of the prosthesis-related complications can be prevented or their impact minimized through optimal prosthesis selection in the individual patient and careful medical management and follow-up after implantation. The purpose of this article is to provide an overview of the current state of knowledge and future perspectives with regard to optimal prosthesis selection and clinical management after valve implantation.
Document Type: Article de recherche
Issue Date: 24 February 2009
Open Access Date: Restricted access
Document version: VoR
This document was published in: Circulation, The Journal of the American Heart Association, Vol. 119 (7), 1034-1048 (2009)
American Heart Association
Alternative version: 10.1161/CIRCULATIONAHA.108.778886
Collection:Articles publiés dans des revues avec comité de lecture

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