Gallium(III) triflate catalyzed diastereoselective mukaiyama aldol reaction by using low catalyst loadings
Authors: | Plancq, Baptiste; Justafort, Lyse Carole; Lafantaisie, Mathieu; Ollevier, Thierry |
Abstract: | A mild method for the diastereoselective Mukaiyama aldol reaction is reported. By using a low loading of the gallium(III) triflate catalyst (down to 0.01 mol-%), the transformation proceeds efficiently to afford the corresponding ß-hydroxy ketones in yields up to 92¿%. To the best of our knowledge, this is the first report of a metal triflate acting as a safe, bench-stable, and slow-releasing source of triflic acid for the Mukaiyama aldol reaction. |
Document Type: | Article de recherche |
Issue Date: | 5 September 2013 |
Open Access Date: | 16 March 2016 |
Document version: | AM |
Permalink: | http://hdl.handle.net/20.500.11794/370 |
This document was published in: | European journal of organic chemistry, Vol. 2013 (29), 6525–6529 (2013) https://doi.org/10.1002/ejoc.201301100 Wiley |
Alternative version: | 10.1002/ejoc.201301100 |
Collection: | Articles publiés dans des revues avec comité de lecture |
Files in this item:
Description | Size | Format | ||
---|---|---|---|---|
2013EJOCversionacceptee.pdf | 468.19 kB | Adobe PDF | ![]() View/Open | |
2013EJOC6225.pdf | Version of Record | 385.84 kB | Adobe PDF | Request a copy |
ejoc_201301100_sm_miscellaneous_information.pdf | Données supplémentaires | 2.13 MB | Adobe PDF | Request a copy |
All documents in CorpusUL are protected by Copyright Act of Canada.