Gallium(III) triflate catalyzed diastereoselective mukaiyama aldol reaction by using low catalyst loadings
| Authors: | Plancq, Baptiste; Justafort, Lyse Carole; Lafantaisie, Mathieu; Ollevier, Thierry |
| Abstract: | A mild method for the diastereoselective Mukaiyama aldol reaction is reported. By using a low loading of the gallium(III) triflate catalyst (down to 0.01 mol-%), the transformation proceeds efficiently to afford the corresponding ß-hydroxy ketones in yields up to 92¿%. To the best of our knowledge, this is the first report of a metal triflate acting as a safe, bench-stable, and slow-releasing source of triflic acid for the Mukaiyama aldol reaction. |
| Document Type: | Article de recherche |
| Issue Date: | 5 September 2013 |
| Open Access Date: | 16 March 2016 |
| Document version: | AM |
| Permalink: | http://hdl.handle.net/20.500.11794/370 |
| This document was published in: | European journal of organic chemistry, Vol. 2013 (29), 6525–6529 (2013) https://doi.org/10.1002/ejoc.201301100 Wiley |
| Alternative version: | 10.1002/ejoc.201301100 |
| Collection: | Articles publiés dans des revues avec comité de lecture |
Files in this item:
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|---|---|---|---|---|
| 2013EJOCversionacceptee.pdf | 468.19 kB | Adobe PDF |  View/Open | |
| 2013EJOC6225.pdf | Version of Record | 385.84 kB | Adobe PDF | Request a copy |
| ejoc_201301100_sm_miscellaneous_information.pdf | Données supplémentaires | 2.13 MB | Adobe PDF | Request a copy |
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