Étude du potentiel clinique d'une sonde échographique transadominale 3D pour son utilisation au moment des traitements de curiethérapie du cancer du col utérin

Authors: St-Amant, Patricia
Advisor: Beaulieu, Luc
Abstract: The present work explores the clinical potential of the adapted prototype of the Clarity AutoScan probe for gynecological brachytherapy use. The goal of this project is to determine whether a 3D transabdominal ultrasound (3DTAUS) can improve treatment planning when combine to computed tomography (CT) compared to CT-based treatment planning. For the purpose of this work, 19 patients were analyzed along the various steps of the study. The two main parts are the contour analysis and the treatment planning analysis. In the first part, images set (magnetic resonance images (MRI), CT and 3DTAUS) of 6 patients were analyzed to determine the visibility of various structures. The comparative high-risk clinical target volume (HR-CTV) contour analysis included 5 patients was performed with 4 images sets (MRI, CT, 3DTAUS and CT-3DTAUS). The HR-CTV volume and lateral dimensions were compared to the reference set, the MRI. Treatment plans optimized on MRI, CT and CT-3DTAUS were elaborated for 5 patients. MRI treatment plans were evaluated on CT and CT-3DTAUS, and CT and CT-3DTAUS were evaluated on MRI. HR-CTV and tandem can be seen on 3DTAUS counter to rectum, sigmoid and ovoids. HRCTV contour analysis shows that 3DTAUS contours, on average, are the ones closer to MRI but with the higher variability. For treatment planning, the treatment plans optimized on CT-3DTAUS are the one closer to MRI, showing improvement to CT plans while combining it to 3DTAUS. For complete 3D treatment planning, 3DTAUS can be used alone. However, the CT-3DTAUS fusion allows treatment plans closer to MRI than CT alone. For the reason, 3DTAUS should be added to the current clinical workflow when MRI is not available.
Document Type: Mémoire de maîtrise
Issue Date: 2017
Open Access Date: 24 April 2018
Permalink: http://hdl.handle.net/20.500.11794/27526
Grantor: Université Laval
Collection:Thèses et mémoires

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