Évaluation fonctionnelle de nouvelles molécules afin de stimuler la production de microparticules et d'augmenter l'épaisseur des tissus reconstruits par génie tissulaire

Authors: Ayoub, Akram
Advisor: Moulin, Véronique
Abstract: Skin production by tissue engineering method is a field whose clinical purpose is expanding. However, many factors need to be improved to enable their extensive use. Our objectives were to evaluate the ability of seaweed extracts and serum molecules to optimize different stages of tissue-engineered skin production. Our hypotheses were that adding seaweed extracts reduces the manufacturing time of reconstructed skin by stimulating the production and the deposition of the extracellular matrix while serum- isolated proteins stimulate the production of microparticles (MP) by the dermal cells, the MP stimulating growth of endothelial cells and thus, potentially, vascularization of the grafts.
Document Type: Mémoire de maîtrise
Issue Date: 2014
Open Access Date: 23 April 2018
Permalink: http://hdl.handle.net/20.500.11794/26047
Grantor: Université Laval
Collection:Thèses et mémoires

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