Synthèse et caractérisation de nanoparticules de fluorures d'yttrium et de fluorure de gadolinium pour des fins d'imagerie médicale

Authors: Blanchette, Maxime
Advisor: Ritcey, Anna Marie
Abstract: The synthesis of yttrium fluoride nanoparticles within reverse microemulsions produces monodisperse population of single crystals of well-defined size and with an octahedral shape. The main advantage of yttrium fluoride is that it can be doped, without loss of crystal structure, in order to confer dopant’s intrinsic properties. Adding a shell of lanthanide fluoride is also possible. Furthermore, the synthesis of nanoparticles for the medical imaging allows to increase the sensor’s sensibility since they contain more active ions then their organic equivalents which, often, contain only one. As part of this project, the lanthanide used as a dopant or to make a shell is gadolinium. Thus, relaxometric properties of different types of nanoparticles, synthetized by the single reverse microemulsion method, are measured and compared. Addition of a silica shell is made in order to increase the colloidal stability of aqueous suspension. Keywords: Gadolinium fluoride, Micelles, Nanoparticles, Reversed microemulsion, Silica shell, Yttrium fluorire.
Document Type: Mémoire de maîtrise
Issue Date: 2014
Open Access Date: 20 April 2018
Grantor: Université Laval
Collection:Thèses et mémoires

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