Development of a single-mode interstitial rotary probe for In Vivo deep brain fluorescence imaging
|Advisor:||Côté, Daniel; De Koninck, Yves|
|Abstract:||This thesis documents the expertise developed by the author at the Centre de recherchede l'Institut universitaire en santé mentale de Québec (CRIUSMQ) in fibered endoscopy, particularly the design and construction of a new kind of optical microscope: ThePanoramic Interstitial Microscope (PIM). Through the juxtaposition of a short piece ofGraded-Index fibre and a prism at the end of a single-mode fibre, laser light is focussedon the side of the probe. To form an image, the latter is quickly spun around its axiswhile it is being pulled vertically by a piezoelectric actuator. This minimally invasivefluorescence rotary interstitial imaging system is an endeavor to limit the damage causedby the probe while imaging enough tissue to provide good context to the user in deep brain optical imaging.|
|Document Type:||Mémoire de maîtrise|
|Open Access Date:||19 April 2018|
|Collection:||Thèses et mémoires|
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