Origine des états actifs spontanés dans le néocortex pendant les oscillations du sommeil

Authors: Chauvette, Sylvain
Advisor: Timofeev, Igor
Abstract: The slow-wave sleep is composed of an alternating period of active and silence state in the thalamocortical system. The mechanisms producing the active and silence state are unknown. In order to investigate the origin of active states, we performed simultaneous intracellular recording of 2 to 4 closely located (< 200μm) neurons and in a distant environment (up to 12mm). In addition, we performed simultaneous local field potentials (up to 16) recordings. These experiments were conducted on anesthetized and nonanesthetized cats. We found that Intrinsically-Bursting cells and deeply located cells have tendency to lead in the onset of the active state. We also observed a high, but similar, variability in the activation delay for closely located cells as well as for distantly located cells. In addition, we observed that the onset of silent state is much more synchronous than the onset of active state.
Document Type: Mémoire de maîtrise
Issue Date: 2006
Open Access Date: 12 April 2018
Permalink: http://hdl.handle.net/20.500.11794/18678
Grantor: Université Laval
Collection:Thèses et mémoires

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