Modulation de l'excitabilité corticospinale et récupération des fonctions locomotrices suite à un accident vasculaire cérébral

Authors: Jouvin, Catherine
Advisor: Schneider, CyrilMalouin, Francine
Abstract: The project aimed to 1) determine, in healthy subjects and persons with chronic stroke, the test-retest reliability of outcome measures related to transcranial magnetic stimulations (TMS) and 2) describe, by means of TMS, the modulation of the corticospinal excitability of the tibialis anterior (TA) as well as test its relationship with clinical measures of locomotor recovery. The TMS outcome measures presenting acceptable reliability level in both groups of participants were the motor threshold, the plateau and maximal values of the motor evoked potentials and the maximal silent period. Cerebral reorganization was observed in the acute stage post-stroke: during the active rehabilitation period, the non lesioned hemisphere’s hyperexcitability decreased and there was a gradual increase of the lesioned hemisphere’s excitability, suggesting a greater control of the paretic TA via the contralateral tracts. A parallel increase in gait speed was also documented thus suggesting a link between a contralateral control and functional recovery.
Document Type: Mémoire de maîtrise
Issue Date: 2006
Open Access Date: 12 April 2018
Grantor: Université Laval
Collection:Thèses et mémoires

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