Tissue engineering of human cornea

Authors: Proulx, StéphanieGuillemette, MaximeCarrier, PatrickAuger, François A.Germain, LucieGiasson, Claude-J.Gaudreault, ManonGuérin, Sylvain
Edited by: Chirila, Traian
Abstract: The cornea is a well-organized tissue composed of three cell types (epithelial, stromal and endothelial cells), each having an important role for its functionality. This chapter will address different tissue engineering approaches to the reconstruction of either partial or full-thickness living corneal substitutes that can be used either as in vitro models for woundhealing studies, or in vivo, eventually replacing the donor cornea for transplantation in humans. Isolation of the proper cells, followed by appropriate culture conditions, and assembly into a three-dimensional tissue construct, are the first steps required for producing a functional corneal substitute.
Document Type: Chapitre d'ouvrage
Issue Date: 27 March 2014
Open Access Date: Restricted access
Document version: VoR
Permalink: http://hdl.handle.net/20.500.11794/16762
This document was published in: Biomaterials and regenerative medicine in ophthalmology
CRC Press
Alternative version: 10.1533/9781845697433.1.150
Collection:Chapitres de livre

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