Skin stem cell identification and culture : a potential tool for rapid epidermal sheet production and grafting

Auteur(s): Germain, LucieMichel, MartineFradette, JulieXu, WenGodbout, Marie-JoséeLi, Hui
Sous la direction de: Rouabhia, Mahmoud
Résumé: Stem cells are fascinating. They are a production factory and give rise to the differentiated tissues. During embryonic development, stem cells multiply and differentiate to generate the cellular diversity necessary for the formation of all tissues. The pluripotentiality of em- bryonic stem cells is very large. Stem cells in the embryo are probably different from those in adults in the sense that some embryonic stem cells are present only transiently and their pluripotentiality is greater than that of adult stem cells which are limited to one compartment, e.g., blood, cutaneous or intestinal epithelial cells. In this chapter, we will concentrate on skin stem cells of postnatal mammals. During the adult life, stem cells are responsible for tissue homeostasis; they proliferate to maintain the number of differentiated cells at a constant level and replace dead cells or cells lost through injury.
Type de document: Chapitre d'ouvrage
Date de publication: 29 janvier 2018
Date de la mise en libre accès: Accès restreint
Version du document: VoR
Lien permanent: http://hdl.handle.net/20.500.11794/16739
Ce document a été publié dans: Skin substitute production by tissue engineering : clinical and fundamental applications
Landes Bioscience
Collection :Chapitres de livre

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