What's New in Human Wound-Healing Myofibroblasts?

Authors: Moulin, Véronique; Garrel, Dominique A.; Auger, François A.; O'Connor-McCourt, Maureen; Castilloux, G.Germain, Lucie
Abstract: During wound healing and fibrocontractive diseases, clinical and experimental investigations have shown that fibroblastic cells acquire some morphological and biochemical features similar to those of smooth muscle cells [33]. These modified fibroblasts, called myofibroblasts, express de novo α-SM actin temporarily during wound healing and permanently in fibrotic situations, such as hypertrophic scars or fibromatosis. Myofibroblasts are thought to be involved in contraction and have been observed in practically all fibrotic conditions involving retraction and reorganization of connective tissues
Document Type: Article de recherche
Issue Date: 1 January 1999
Open Access Date: 24 January 2018
Document version: VoR
Permalink: http://hdl.handle.net/20.500.11794/16612
This document was published in: Current topics in pathology, Vol. 93, 123-133 (1999)
https://doi.org/10.1007/978-3-642-58456-5_13
springerLink
Alternative version: 10.1007%2F978-3-642-58456-5_13
10339905
Collection:Articles publiés dans des revues avec comité de lecture

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