Spray and freeze drying of human milk on the retention of immunoglobulins (IgA, IgG, IgM)

Auteur(s): Castro-Albarràn, Jorge; Aguilar-Uscanga, Blanca Rosa; Calon, FrédéricSt-Amour, Isabelle; Solís-Pacheco, Josué; Saucier, LindaRatti, Cristina
Résumé: Several freeze-drying and spray-drying methods were investigated in relation to the retention of immunoglobulins (Ig) A, IgG, and IgM. Spray drying produced human milk powders with 2% humidity and a good retention of IgG (>88%) and IgM (∼70%). However, only 38% of IgA remained after spray drying. For freeze drying, only the highest heating plate temperature used in this study (40°C) brought IgA content down to 55% in powder with 1.75% residual humidity, whereas milk samples undergoing lower temperatures had higher preservation rates (75% for IgA and 80% for IgG and IgM) and higher residual moisture contents. From these results, it can be concluded that IgA is the most sensitive Ig lost during drying processing of human milk. The best method to generate human milk powders without a significant loss of Ig was thus freeze drying at 30°C heating plate temperature, which accelerated the process compared to lower processing temperatures, but still had good overall Ig retention.
Type de document: Article de recherche
Date de publication: 7 mars 2016
Date de la mise en libre accès: 22 janvier 2018
Version du document: AM
Lien permanent: http://hdl.handle.net/20.500.11794/16541
Ce document a été publié dans: Drying technology : an international journal, Vol. 34 (15), 1801–1809 (2016)
https://doi.org/10.1080/07373937.2016.1141781
M. Dekker
Autre version disponible: 10.1080/07373937.2016.1141781
Collection :Articles publiés dans des revues avec comité de lecture

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