Copper-catalyzed carbenoid insertion reactions of a-diazoesters and a-diazoketones into Si–H and S–H bonds

Authors: Keipour, HodaJalba, AngelaDelage-Laurin, LéoOllevier, Thierry
Abstract: An efficient copper-catalyzed carbenoid insertion reaction of a-diazo carbonyl compounds into Si–H and S–H bonds was developed. A wide range of a-silylesters and a-thioesters was obtained in high yields (up to 98%) from a-diazoesters using 5 mol % of a simple copper(I) salt as catalyst. Using 0.05 mol % of the same catalyst, a-diazoketones led to a-silylketones in low to good yields (up to 70%).
Document Type: Article de recherche
Issue Date: 28 January 2017
Open Access Date: 28 January 2018
Document version: AM
This document was published in: Journal of organic chemistry, (2017)
American Chemical Society
Alternative version: 10.1021/acs.joc.6b02998
Collection:Articles publiés dans des revues avec comité de lecture

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