Enantioselective aromatic sulfide oxidation and tandem kinetic resolution using aqueous H2O2 and chiral iron Bis(oxazolinyl)bipyridine catalysts

Authors: Jalba, AngelaRégnier, NoémieOllevier, Thierry
Abstract: An efficient method for the oxidation of aromatic sulfides was developed using aqueous H2O2 catalyzed by in situ-generated chiral Fe/6,6'-bis(oxazolinyl)-2,2'-bipyridine (bipybox) complex. The corresponding sulfoxides were obtained in high enantio-selectivities (up to 98.5:1.5 er) and good yields (up to 61%) when the mono-oxidation of the sulfides was performed in combination with the kinetic resolution of the sulfoxide into the sulfone.
Document Type: Article de recherche
Issue Date: 27 December 2016
Open Access Date: 27 December 2017
Document version: AM
Permalink: http://hdl.handle.net/20.500.11794/12968
This document was published in: European Journal of Organic Chemistry
Alternative version: 10.1002/ejoc.201601597
Collection:Articles publiés dans des revues avec comité de lecture

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