Search

Current filters:

Add filters:

 

Results 41-50 of 2821 (Search time: 0.037 seconds).

Issue DateTitleAuthor(s)TypeAccess
1 March 2001Intramolecular cyclization of N-phenyl N’(2-chloroethyl)ureas leads to active N-phenyl-4,5-dihydrooxazol-2-amines alkylating b-tubulin Glu198 and prohibitin Asp40Trzeciakiewicz, Anna; Fortin, Sébastien; Moreau, Emmanuel; C. Gaudreault, René; Lacroix, Jacques M.; Chambon, Christophe; Communal, Yves; Chezal, Jean-Michel; Miot-Noirault, Elisabeth; Bouchon, Bernadette; Degoul, FrançoiseArticle de rechercheOpen access
1 March 2015Novel cytocidal substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates and benzenesulfonamides with affinity to the colchicine-binding site : is the phenyl 2-imidazolidinone moiety a new haptophore for the design of new antimitotics?Fortin, Sébastien; Wei, Lianhu; Kotra, Lakshmi P.; C. Gaudreault, RenéArticle de rechercheOpen access
17 December 2011Synthesis, antiproliferative activity and estrogen receptor α affinity of novel estradiol-linked platinum(II) complex analogs to carboplatin and oxaliplatin. Potential vector complexes to target estrogen-dependent tissuesSaha, Pijus; Descôteaux, Caroline; Brasseur, Kevin; Fortin, Sébastien; Leblanc, Valérie; Parent, Sophie; Asselin, Éric; Bérubé, GervaisArticle de rechercheOpen access
30 August 2011Substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonamides as antimitotics. Antiproliferative, antiangiogenic and antitumoral activity, and quantitative structure-activity relationshipsFortin, Sébastien; Wei, Lianhu; Moreau, Emmanuel; Lacroix, Jacques M.; Côté, Marie-France; Petitclerc, Éric; Kotra, Lakshmi P.; C. Gaudreault, RenéArticle de rechercheOpen access
23 May 2011Design, synthesis, biological evaluation and structure-activity relationships of substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new tubulin inhibitors mimicking combretastatin A-4Fortin, Sébastien; Wei, Lianhu; Moreau, Emmanuel; Lacroix, Jacques M.; Côté, Marie-France; Petitclerc, Éric; Kotra, Lakshmi P.; C. Gaudreault, RenéArticle de rechercheOpen access
18 January 2011Characterization of the covalent binding of N-phenyl-N'-(2-chloroethyl)ureas to β-tubulin : importance of glutamic acid 198 in microtubule stabilityFortin, Sébastien; Bouchon, Bernadette; Chambon, Christophe; Lacroix, Jacques M.; Moreau, Emmanuel; Chezal, Jean-Michel; Degoul, Françoise; C. Gaudreault, RenéArticle de rechercheUpon request
8 April 2010Quick and simple detection technique to assess the binding of antimicrotubule agents to the colchicine-binding siteFortin, Sébastien; Lacroix, Jacques M.; Côté, Marie-France; Moreau, Emmanuel; Petitclerc, Éric; C. Gaudreault, RenéArticle de rechercheOpen access
15 August 2013New platinum(II) complexes conjugate at position 7α of 17β-acetyl-testosterone as new combi-molecules against prostate cancer : design, synthesis, structure-activity relationships and biological evaluationFortin, Sébastien; Brasseur, Kevin; Morin, Nathalie; Asselin, Éric; Bérubé, GervaisArticle de rechercheOpen access
7 May 2013Advances in the development of hybrid anticancer drugsFortin, Sébastien; Bérubé, GervaisArticle de rechercheOpen access
15 July 2012Design, synthesis, cytocidal activity and estrogen receptor a affinity of doxorubicin conjugates at 16α-position of estrogen for site-specific treatment of estrogen receptor-positive breast cancersSaha, Pijus; Fortin, Sébastien; Leblanc, Valérie; Parent, Sophie; Asselin, Éric; Bérubé, GervaisArticle de rechercheOpen access