Corpus^UL

Background: Elevated Lp(a) (Lipoprotein(a)) levels are associated with coronary artery disease (CAD), ischemic stroke (IS), and calcific aortic valve stenosis (CAVS). Studies investigating the association between Lp(a) levels and these diseases in women have yielded inconsistent results. Methods: To investigate the association of Lp(a) with sex-specific cardiovascular outcomes, we determined the association between genetically predicted Lp(a) levels (using 27 single nucleotide polymorphism...

We propose and experimentally demonstrate a polarization-insensitive single sideband modulator based on silicon microring modulators (MRM). The proposed modulator splits and modulates the two orthogonal polarization states of an input laser in a loopback structure, with an on-chip silicon polarization splitter rotator (PSR), overcoming the polarization dependence of the silicon photonic modulator. The IQ configuration of the modulator enables single sideband modulation, thus improving t...

BACKGROUND: Low rest transaortic flow rate (FR) has been shown previously to predict mortality in low-gradient aortic stenosis. However limited prognostic data exists on stress FR during low-dose dobutamine stress echocardiography. We aimed to assess the value of stress FR for the detection of aortic valve stenosis (AS) severity and the prediction of mortality. METHODS: This is a multicenter cohort study of patients with reduced left ventricular ejection fraction and low-gradient aortic s...