Publication :
Why and how to measure aortic valve calcification in patients with aortic stenosis

Pas de vignette d'image disponible
Date
2019-09-02
Auteurs
Pawade, Tania
Sheth, Tej
Dweck, Marc
Direction de publication
Direction de recherche
Titre de la revue
ISSN de la revue
Titre du volume
Éditeur
Elsevier
Projets de recherche
Structures organisationnelles
Numéro de revue
Résumé

The first-line evaluation of aortic stenosis severity is Doppler echocardiography. However, in up to 40% of patients, resting echocardiographic assessment of aortic stenosis severity is discordant, leading to clinical uncertainty. Interest has therefore grown in aortic valve calcium scoring by multidetector computed tomography (CT-AVC) as an alternative load independent assessment of aortic stenosis severity. This paper will briefly review the pathophysiology of aortic stenosis and the crucial role that calcification plays in driving progressive obstruction of the valve. Subsequently, it will describe published reports that have investigated CT-AVC, validating this parameter against histology, and establishing its diagnostic accuracy versus echocardiography as well as its powerful independent prognostic capability. Finally, this review seeks to provide a practical guide about how best to acquire and interpret CT-AVC with a close focus on potential pitfalls and how these might be best avoided as this technique becomes more widely adopted in to clinical practice.

Description
Revue
JACC. Cardiovascular imaging, Vol. 12 (9), 1835-1848 (2019)
DOI
10.1016/j.jcmg.2019.01.045
URL vers la version publiée
Mots-clés
Aortic stenosis , Aortic valve calcification , Computed tomography
Citation
Type de document
article de recherche