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Cognitive structure from childhood to adulthood in kindreds densely affected by schizophrenia and bipolar disorder

bul.description.provenanceec spbfr
bul.rights.dateAccepPubl2015-07-23fr
bul.rights.periodeEmbargoforeverfr
bul.rights.raisonEmbargoInfiniPour que le document soit diffusé en libre accès, en accord avec le délai prescrit par l’éditeur de Psychiatry research, il faudrait déposer la version acceptée pour publication, incluant toutes les modifications demandées, mais sans la mise en page de la revue. Pour ce faire, effectuez une demande de modification à l’aide de la liste des dépôts diffusés à partir du tableau de suivi.fr
bul.rights.typeDatedatePublicationfr
dc.contributor.authorMérette, Chantal
dc.contributor.authorJomphe, Valérie
dc.contributor.authorMoreau, Isabel
dc.contributor.authorGilbert, Elsa
dc.contributor.authorPaccalet, Thomas
dc.contributor.authorRoy, Marc-André
dc.contributor.authorRouleau, Nancie
dc.contributor.authorCellard, Caroline
dc.contributor.authorMaziade, Michel
dc.date.accessioned2020-07-29T11:04:56Z
dc.date.available9999-12-31
dc.date.issued2015-07-23
dc.description.abstractThe developmental aspects of cognitive structures from childhood until adulthood and across different levels of risk for psychopathology have been little studied. The aim of the current study was to explore the cognitive factorial structure in subsamples from highly familial and densely affected kindreds of schizophrenia and bipolar disorder – i.e. affected adult members, non-affected adult members and high-risk youth. The same neuropsychological battery was administered in a sample of 480 participants: schizophrenia and bipolar patients (n=51), young high-risk offspring (n=61), non-affected adult relatives of patients (n=96), and controls (n=272). Exploratory Factorial Analysis was performed in the control sample and yielded a 5-factor solution: verbal comprehension, processing speed/working memory, visual learning and memory, verbal learning and memory, reasoning and problem solving. Confirmatory factor analysis indicated that the hierarchical 5-factor solution was well suited for the young high-risk offspring, the non-affected adult relatives of patient and the patients. A hierarchical model with a “g” factor was a good fit for all subsamples. These results suggest that cognitive impairments may aggregate in highly familial individuals.fr
dc.identifier.doi10.1016/j.psychres.2015.07.063fr
dc.identifier.issn0165-1781fr
dc.identifier.pubmed26233828fr
dc.identifier.urihttp://hdl.handle.net/20.500.11794/39876
dc.languageengfr
dc.publisherElsevier Ltd.fr
dc.rightshttp://purl.org/coar/access_right/c_16ec
dc.subjectNeuropsychologyfr
dc.subjectExploratory Factorial Analysisfr
dc.subjectConfirmatory Factorial Analysisfr
dc.subjectg Factorfr
dc.subjectChildrenfr
dc.subjectAdolescentsfr
dc.subjectAdultsfr
dc.subject.rvmCognition chez l'enfantfr
dc.subject.rvmNeuropsychologiefr
dc.subject.rvmFacteur général (Psychologie)fr
dc.subject.rvmTroubles bipolairesfr
dc.subject.rvmSchizophréniefr
dc.titleCognitive structure from childhood to adulthood in kindreds densely affected by schizophrenia and bipolar disorderfr
dc.typearticle de recherche
dc.type.legacyCOAR1_1::Texte::Périodique::Revue::Contribution à un journal::Article::Article de recherchefr
dcterms.bibliographicCitationPsychiatry research, Vol. 229 (1-2), 101-108 (2015)fr
dspace.accessstatus.time2023-01-28 18:03:11
dspace.entity.typePublication
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rioxxterms.project#950-200810; #MOP-74430fr
rioxxterms.project.funder-nameCanadian Institutes of Health Researchfr
rioxxterms.project.funder-nameCanada Research Chair in psychiatric geneticsfr
rioxxterms.versionVoRfr
rioxxterms.version-of-recordhttps://doi.org/10.1016/j.psychres.2015.07.063fr
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