Publication : Influence of the menstrual cycle on the timing of acute coronary events in premenopausal women.
bul.description.provenance | mcpro ----- spbar | |
bul.rights.raisonEmbargoInfini | Pour que le document soit diffusé en libre accès, en accord avec le délai prescrit par l’éditeur de American Journal of Medicine, il faudrait déposer la version acceptée pour publication, incluant toutes les modifications demandées, mais sans la mise en page de la revue. Pour ce faire, effectuez une demande de modification à l’aide du formulaire : https://www.bibl.ulaval.ca/cgi-bin/demmodifdepot-corpus.pl | |
dc.contributor.author | Hamelin, Bettina | |
dc.contributor.author | Méthot, Julie | |
dc.contributor.author | Arsenault, Marie | |
dc.contributor.author | Pilote, Sylvie | |
dc.contributor.author | Poirier, Paul | |
dc.contributor.author | Plante, Sylvain | |
dc.contributor.author | Bogaty, Peter | |
dc.date.accessioned | 2022-12-07T21:16:49Z | |
dc.date.available | 2022-12-07T21:16:49Z | |
dc.date.issued | 2003-05-10 | |
dc.description.abstract | During their reproductive years, women have a low incidence of coronary artery disease, which increases markedly 10 to 15 years after menopause. It has long been hypothesized that this increased risk is at least in part due to the absence of female hormones, in particular, 17β-estradiol. This hypothesis was supported by data from epidemiological studies, which suggested that hormone replacement therapy would protect postmenopausal women from coronary artery disease. However, recent placebo-controlled trials designed to test the cardioprotective effects of a regimen of estrogens plus progestin have found no reduction in cardiovascular events or progression of angiographic lesions. Nevertheless, acute administration of 17β-estradiol affects the vasculature by modulating the nitric oxide–L-arginine pathway, and improves endothelial function and prolongs the time to ST-segment depression and exercise time, in postmenopausal women with coronary artery disease. These data suggest that the acute effects of 17β-estradiol could subside rapidly when levels are low during menses. Therefore, we sought to determine whether premenopausal women would be at greater risk of developing an acute coronary event when blood levels of 17β-estradiol levels are low during the menstrual cycle. | |
dc.identifier.doi | 10.1016/s0002-9343(03)00051-2 | |
dc.identifier.issn | 0002-9343 | |
dc.identifier.other | 12753884 | |
dc.identifier.uri | http://hdl.handle.net/20.500.11794/105783 | |
dc.language | eng | |
dc.language.iso | en | |
dc.publisher | New York, NY : Excerpta Medica, Inc. | |
dc.rights | http://purl.org/coar/access_right/c_16ec | |
dc.subject | Menstrual cycle | en_US |
dc.subject | Acute coronary | en_US |
dc.subject | Events women | en_US |
dc.subject | 17β-estradiol | en_US |
dc.subject.rvm | Cycle menstruel | |
dc.subject.rvm | Œstradiol | |
dc.subject.rvm | Périménopause | |
dc.subject.rvm | Artères coronaires -- Maladies | |
dc.title | Influence of the menstrual cycle on the timing of acute coronary events in premenopausal women. | |
dc.type | article de recherche | |
dcterms.bibliographicCitation | American Journal of Medicine, Vol. 14 (7), 599-602 (2003) | |
dcterms.dateAccepted | 2002-11-27 | |
dspace.accessstatus.time | 2024-03-19 18:00:37 | |
dspace.entity.type | Publication | |
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rioxxterms.version | Version of Record (VoR) | |
rioxxterms.version-of-record | https://doi.org/10.1016/S0002-9343(03)00051-2 |
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