Publication :
Functional and structural aging of the speech sensorimotor neural system : fMRI evidence

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Date
2013-03-21
Auteurs
Dick, Anthony Steven
Small, Steven L.
Direction de publication
Direction de recherche
Titre de la revue
ISSN de la revue
Titre du volume
Éditeur
Elsevier
Projets de recherche
Structures organisationnelles
Numéro de revue
Résumé
The ability to perceive and produce speech undergoes important changes in late adulthood. The goal of the present study was to characterize functional and structural age-related differences in the cortical network that support speech perception and production, using magnetic resonance imaging, as well as the relationship between functional and structural age-related changes occurring in this network. We asked young and older adults to observe videos of a speaker producing single words (perception), and to observe and repeat the words produced (production). Results show a widespread bilateral network of brain activation for Perception and Production that was not correlated with age. In addition, several regions did show age-related change (auditory cortex, planum temporale, superior temporal sulcus, premotor cortices, SMA-proper). Examination of the relationship between brain signal and regional and global gray matter volume and cortical thickness revealed a complex set of relationships between structure and function, with some regions showing a relationship between structure and function and some not. The present results provide novel findings about the neurobiology of aging and verbal communication.
Description
Revue
Neurobiology of Aging, Vol. 34 (8), 1935–1951 (2013)
DOI
10.1016/j.neurobiolaging.2013.02.004
URL vers la version publiée
Mots-clés
Normal aging , Speech perception , Speech production , Brain reserve capacity , Surface-based cortical thickness , Gray matter volume , MRI , Language
Citation
Type de document
article de recherche