Publication :
Human saphenous vein endothelial cell adhesion and expansion on micropatterned polytetrafluoroethylene

Notice brève
bul.description.provenancelf spbfr
bul.rights.dateAccepPubl2012-08-31fr
bul.rights.periodeEmbargoP1Yfr
bul.rights.typeDatedatePublicationfr
dc.contributor.authorBoivin, Marie-Claude
dc.contributor.authorLaroche, Gaétan
dc.contributor.authorHoesli, Corinne A.
dc.contributor.authorLagueux, Jean
dc.contributor.authorBareille, Reine
dc.contributor.authorRémy-Zolghadri, Murielle
dc.contributor.authorChevallier, Pascale
dc.contributor.authorBordenave, Laurence
dc.contributor.authorDurrieu, Marie-Christine
dc.date.accessioned2019-07-23T19:54:11Z
dc.date.available2019-07-23T19:54:11Z
dc.date.issued2012-08-31
dc.description.abstractIntimal hyperplasia and thrombosis are responsible for the poor patency rates of small-diameter vascular grafts. These complications could be avoided by a rapid and strong adhesion of endothelial cells to the prosthetic surfaces, which typically consist of expanded polytetrafluoroethylene (PTFE) for small-diameter vessels. We have previously described two peptide micropatterning strategies that increase the endothelialization rates of PTFE. The micropatterns were generated either by inkjet printing 300 μm squares or by spraying 10.1 ± 0.1 μm diameter droplets of the CGRGDS cell adhesion peptide, while the remaining surface was functionalized using the CWQPPRARI cell migration peptide. We now directly compare these two micropatterning strategies and examine the effect of hydrodynamic stress on human saphenous vein endothelial cells grown on the patterned surfaces. No significant differences in cell adhesion were observed between the two micropatterning methods. When compared to unpatterned surfaces treated with a uniform mixture of the two peptides, the cell expansion was significantly higher on sprayed or printed surfaces after 9 days of static cell culture. In addition, after 6 h of exposure to hydrodynamic stress, the cell retention and cell cytoskeleton reorganization on the patterned surfaces was improved when compared to untreated or random treated surfaces. These results indicate that micropatterned surfaces lead to improved rates of PTFE endothelialization with higher resistance to hydrodynamic stress.fr
dc.identifier.doi10.1002/jbm.a.34367fr
dc.identifier.issn1549-3296fr
dc.identifier.pubmed22941911fr
dc.identifier.urihttp://hdl.handle.net/20.500.11794/35601
dc.languageengfr
dc.publisherWileyfr
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.subjectSurface engineeringfr
dc.subjectMicropatterningfr
dc.subjectPeptides graftingfr
dc.subjectEndothelial cellsfr
dc.subjecthydrodynamic conditionsfr
dc.subjectCell reorganizationfr
dc.subject.rvmCellules endothéliales vasculairesfr
dc.subject.rvmCellules -- Adhésivitéfr
dc.subject.rvmPolytétrafluoréthylènefr
dc.subject.rvmPeptidesfr
dc.subject.rvmVeines saphènesfr
dc.titleHuman saphenous vein endothelial cell adhesion and expansion on micropatterned polytetrafluoroethylenefr
dc.typearticle de recherche
dc.type.legacyCOAR1_1::Texte::Périodique::Revue::Contribution à un journal::Article::Article de recherchefr
dcterms.bibliographicCitationJournal of biomedical materials research. Part A, Vol. 101A (3), 694-703 (2013)fr
dspace.accessstatus.time2023-03-28 18:01:37
dspace.entity.typePublication
relation.isAuthorOfPublication07aeedb9-817b-47b2-ae40-d28f00c24821
relation.isAuthorOfPublication7207871e-32e9-4680-a0f1-6ce126aebe57
relation.isAuthorOfPublication858cfce0-ed27-4b69-95fa-c9ef536b8744
relation.isAuthorOfPublicationc08cb735-d916-493f-a106-d08d2426f1f0
relation.isAuthorOfPublicationd0403eea-d3d8-49d9-9e13-542359c24b6d
relation.isAuthorOfPublicationeaba009b-0f2b-4d24-8a89-43d89fce30a9
relation.isAuthorOfPublication.latestForDiscovery07aeedb9-817b-47b2-ae40-d28f00c24821
relation.isResourceTypeOfPublication4c433ef5-3937-4530-8252-cca17d715747
relation.isResourceTypeOfPublication.latestForDiscovery4c433ef5-3937-4530-8252-cca17d715747
rioxxterms.project.funder-nameNatural Sciences and Engineering Research Council of Canadafr
rioxxterms.project.funder-nameCentre Québécois sur les Matériaux Fonctionnelsfr
rioxxterms.project.funder-nameNeusentisfr
rioxxterms.project.funder-namePfizerfr
rioxxterms.versionAMfr
rioxxterms.version-of-recordhttps://doi.org/10.1002/jbm.a.34367fr
Fichiers
Bundle original
Voici les éléments 1 - 1 sur 1
Vignette d'image
Nom :
Human saphenous vein endothelial cell adhesion and expansion on micropatterned polytetrafluoroethylene.pdf
Taille :
1.59 MB
Format :
Adobe Portable Document Format
Description :
Télécharger
Collections
Articles publiés dans des revues avec comité de lecture