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Publication :
Effectiveness and content analysis of interventions to enhance oral antidiabetic drug adherence in adults with type2 diabetes : systematic review and meta-analysis

bul.description.provenanceec spbfr
bul.rights.dateAccepPubl2015-05-23fr
bul.rights.periodeEmbargoforeverfr
bul.rights.raisonEmbargoInfiniPour que le document soit diffusé en libre accès, en accord avec le délai prescrit par l’éditeur de Value in Health, il faudrait déposer la version acceptée pour publication, incluant toutes les modifications demandées, mais sans la mise en page de la revue. Pour ce faire, effectuez une demande de modification à l’aide de la liste des dépôts diffusés à partir du tableau de suivi.fr
bul.rights.typeDatedatePublicationfr
dc.audience.peerreview1fr
dc.contributor.authorGrégoire, Jean-Pierre
dc.contributor.authorBruin, Marijn de
dc.contributor.authorVézina-Im, Lydi-Anne
dc.contributor.authorGuillaumie, Laurence
dc.contributor.authorPérez Herrera, Norma Maria
dc.contributor.authorZomahoun, Hervé Tchala Vignon
dc.contributor.authorMoisan, Jocelyne
dc.contributor.authorGuénette, Line
dc.date.accessioned2017-12-05T13:41:24Z
dc.date.available9999-12-31
dc.date.issued2015-05-23
dc.description.abstractObjectives: To estimate the pooled effect size of oral antidiabetic drug (OAD) adherence-enhancing interventions and to explore which of the behavior change techniques (BCTs) applied in the intervention groups modified this pooled intervention effect size. Methods: We searched relevant studies published until September 3, 2013, on MEDLINE, Embase, PsycInfo, the Cochrane Library, CINAHL, Current Contents Connect, and Web of Science. Selected studies were qualitatively synthesized, and those of at least medium quality were included in the meta-analysis. A random-effects model was used to pool effectiveness (Hedges’s g) and to examine heterogeneity (Higgins I2). We also explored the influence on the pooled effectiveness of unique intervention BCTs (those delivered to the intervention groups but not control groups in a trial) by estimating their modifying effects. Results: Fourteen studies were selected for the qualitative synthesis and 10 were included in the meta-analysis. The pooled effectiveness of the interventions was 0.21 (95% confidence interval −0.05 to 0.47; I2 = 82%). Eight unique BCTs were analyzed. “Cope with side effects” (P = 0.003) and “general intention formation” (P = 0.006) had a modifying effect on the pooled effectiveness. The pooled effectiveness of the interventions in which “cope with side effects” was applied was moderate (0.64; 95% confidence interval 0.31–0.96; I2 = 56%). Conclusions: The overall effectiveness of OAD adherence-enhancing interventions that have been tested is small. Helping patients cope with side effects or formulate desired treatment outcomes could have an impact on the effectiveness of OAD adherence-enhancing interventions. Only those interventions that include helping patients to cope with side effects appear to be particularly effective in improving OAD adherence.fr
dc.identifier.doi10.1016/j.jval.2015.02.017fr
dc.identifier.issn1098-3015fr
dc.identifier.pubmed26091607fr
dc.identifier.urihttp://hdl.handle.net/20.500.11794/16085
dc.languageengfr
dc.publisherElsevierfr
dc.rightshttp://purl.org/coar/access_right/c_16ec
dc.subjectAdherencefr
dc.subjectDiabetesfr
dc.subjectOral antidiabetic drugfr
dc.subjectMeta-analysisfr
dc.subjectInterventionfr
dc.subject.rvmDiabète non insulinodépendant -- Traitementfr
dc.subject.rvmHypoglycémiantsfr
dc.subject.rvmDiabétiquesfr
dc.titleEffectiveness and content analysis of interventions to enhance oral antidiabetic drug adherence in adults with type2 diabetes : systematic review and meta-analysisfr
dc.typearticle de synthèse
dc.type.legacyCOAR1_1::Texte::Périodique::Revue::Contribution à un journal::Article::Article de synthèsefr
dcterms.bibliographicCitationValue in Health, Vol. 18 (4), 530–540 (2015)fr
dspace.accessstatus.time2024-03-23 18:03:18
dspace.entity.typePublication
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rioxxterms.project.funder-nameLaval University Chair on Adherence to Treatmentsfr
rioxxterms.versionVersion of Record (VoR)fr
rioxxterms.version-of-recordhttps://doi.org/10.1016/j.jval.2015.02.017fr

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