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Robitaille, Julie

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Robitaille

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Julie

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Université Laval. Institut sur la nutrition et les aliments fonctionnels

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Voici les éléments 1 - 10 sur 37
  • PublicationRestreint
    The PPAR-gamma P12A polymorphism modulates the relation between dietary fat intake and components of the metabolic syndrome : results from the Quebec Family Study
    (Blackwell-synergy, 2003-03-10) Pérusse, Louis; Vohl, Marie-Claude; Després, Jean-Pierre; Robitaille, Julie
    The metabolic syndrome is a complex disorder characterized by an atherogenic dyslipidemia resulting from the interaction between genetic and nutritional factors. The objective of this study was to examine in a cohort of 720 adults participating in the Québec Family Study (QFS) whether dietary fat interacts with the P12A polymorphism in the gene encoding the peroxisome proliferator‐activated receptor‐gamma (PPAR‐γ), a nuclear factor that regulates lipid and glucose homeostasis. Carriers of the A12 allele had a higher body mass index (BMI), waist circumference, fat mass as well as subcutaneous adipose tissue and visceral adipose tissue (VAT) areas both assessed by computed tomography than P12/P12 homozygotes. Total fat and saturated fat intakes estimated from a 3‐day food record were significantly correlated with several components of the metabolic syndrome in P12/P12 homozygotes. None of these expected associations were observed among carriers of the A12 allele. Furthermore, in a model including the PPAR‐γ P12A polymorphism, fat intake, age and gender, PPAR‐γ P12A and its interaction with fat intake were associated with BMI and waist circumference. Similar results were obtained when saturated fat intake replaced total fat intake into the model. When the two genotype groups were further classified into quartiles of total fat or saturated fat intake and their characteristics compared, an increase in fat intake was associated with an increase in waist circumference in P12/P12 homozygotes but not in A12 carriers. There was no difference in the waist circumference in carriers of the A12 allele whether the fat or the saturated fat intake was high or low. These results suggest that the PPAR‐γ P12A polymorphism can modulate the association between dietary fat intake and components of the metabolic syndrome.
  • PublicationAccès libre
    Postnatal prevention of childhood obesity in offspring prenatally exposed to gestational diabetes mellitus : where are we now?
    (S. Karger, 2017-08-23) Perron, Julie; Mercier, Roxanne; Weisnagel, John; Kearney, Michèle; Marc-Sériès, Isabelle; Robitaille, Julie; Tchernof, André; Dugas, Camille
    Children exposed to gestational diabetes mellitus (GDM) in utero are at high risk of developing many health problems such as obesity. There is an urgent need to find new strategies to prevent obesity development among high-risk populations such as those children. Accordingly, the aim of this review was to summarize current knowledge on the postnatal prevention of childhood obesity in offspring born from mothers with GDM. Specifically, this review addresses the impact of breastfeeding, complementary feeding practices as well as dietary intake and physical activity during childhood on obesity risk of children exposed to GDM in utero. Furthermore, breast milk composition of diabetic mothers and its potential impact on growth is discussed. According to the available literature, breastfeeding may reduce obesity risk in children exposed to GDM in utero but a longer duration seems necessary to achieve its protective effect against obesity. Detailed analysis of breast milk composition of mothers with GDM will be necessary to fully understand the relationship between breastfeeding and obesity in this specific population. This review highlights the need for more studies addressing the impact of complementary feeding practices and lifestyle habits during childhood on obesity risk of children exposed to GDM in utero.
  • PublicationAccès libre
    Relative validity of a web-based, self-administered, 24-hour dietary recall to evaluate adherence to Canadian dietary guidelines
    (Elsevier Science, 2018-05-24) Lafrenière, Jacynthe; Laramée, Catherine; Robitaille, Julie; Lamarche, Benoît; Lemieux, Simone
    Objectives: A new, web-based, 24-h recall (R24 W) was developed and programmed to assess adherence to Canadian dietary guidelines by automatically generating the Canadian Healthy Eating Index 2007 (C-HEI 2007). The aim of the present study was to determine the relative validity of the R24 W in terms of its ability to generate C-HEI 2007 scores that match those derived from a food record (FR). Methods: A total of 57 women and 50 men filled a 3-d FR and three 24-h food recalls with the R24 W. C-HEI 2007 was calculated with both dietary assessment tools and compared using de-attenuated correlations and kappa scores. Internal validity (correlations between total score and components) and external validity (comparison of the C-HEI 2007 by sex and age groups) were compared between the two dietary assessment methods. Results: The average C-HEI 2007 score obtained with the R24 W (59.4 ± 11.8) was significantly lower than the one obtained with the FR (62.6 ± 11.1). However, the de-attenuated correlation coefficient between C-HEI 2007 obtained either with R24 W or FR was 0.80 (P < 0.01) and 91.6% of participants were classified in the same or adjacent quartile of C-HEI 2007 with both tools. Women obtained a higher C-HEI 2007 mean score (P < 0.01) with both methods and older adults (age: >51 y) received a higher score than younger adults (age: 18-30 y; P < 0.01) with the R24 W but not with the FR (P = 0.22). Conclusions: Although the R24 W yields lower C-HEI 2007 scores compared with data from FR, the classification of individuals was highly consistent between the two measurements.
  • PublicationAccès libre
    Individuals with self-determined motivation for eating have better overall diet quality : Results from the PREDISE study
    (Academic Press, 2021-05-24) Carbonneau, Élise; Pelletier, Luc; Bégin, Catherine; Lamarche, Benoît; Bélanger, Mathieu; Provencher, Véronique; Desroches, Sophie; Robitaille, Julie; Vohl, Marie-Claude; Couillard, Charles; Bouchard, Luigi; Houle, Julie; Langlois, Marie-France; Rabasa-Lhoret, Rémi; Corneau, Louise; Lemieux, Simone; Corneau, Louise
    The study aimed at documenting motivational orientations for the regulation of eating as defined by self-determination theory and their association with sociodemographic characteristics and overall diet quality. As part of the PREDISE study, French-speaking women (n = 550) and men (n = 547), aged 18-65 years, living in the Province of Québec, Canada, completed online validated questionnaires. The Regulation of Eating Behavior Scale, based on the self-determination theory, assessed self-determined and non-self-determined motivation to regulate one's eating behavior. Three web-based 24-h food recalls were completed and used to compute the Canadian Healthy Eating Index 2007 (C-HEI), an indicator of the overall adherence to Canadian guidelines for healthy eating. Multiple linear regressions were performed to assess how regulation styles are associated with the C-HEI. Model 1 included no covariate, model 2 included sociodemographic covariates, and fully adjusted model 3 included as covariates sociodemographic variables as well as variables that were previously associated with diet quality, namely nutrition knowledge and social support for healthy eating. Women (p < 0.0001), older individuals (p = 0.0002), those with a higher education level (p < 0.0001), and non-smokers (p < 0.0001) reported higher self-determined motivation score than their counterparts. Self-determined motivation was positively (model 1: B = 4.67, p < 0.0001; model 2: B = 3.82, p < 0.0001; model 3: B = 3.61, p < 0.0001) and non-self-determined motivation was negatively (model 1: B = -1.62, p = 0.0009; model 2: B = -1.63, p = 0.0006; model 2: B = -1.49, p = 0.0022) associated with C-HEI. The present study suggests that some subgroups of the general adult population show more self-determined motivation for eating, which is associated with a better diet quality independently of individual characteristics and other individual and social determinants of healthy eating. Strategies to help individuals internalize the regulation of eating should be further investigated.
  • PublicationAccès libre
    Risks of nutrigenomics and nutrigenetics? What the scientists say
    (Springer, 2013-11-29) Hurlimann, Thierry; Vohl, Marie-Claude; Menuz, Vincent; Robitaille, Julie; Graham, Janice E.; Godard, Béatrice
    Nutrigenomics and nutrigenetics (hereafter NGx) have stimulated expectations for beneficial applications in public health and individuals. Yet, the potential achievability of such promise is not without socioethical considerations that challenge NGx implementation. This paper focuses on the opinions of NGx researchers about potential risks raised by NGx. The results of an online survey show that these researchers (n = 126) are fairly confident about the potential benefits of NGx, and that most downplay its potential risks. Researchers in this field do not believe that NGx will reconfigure foods as medication or transform the conception of eating into a health hazard. The majority think that NGx will produce no added burden on individuals to get tested or to remain compliant with NGx recommendations, nor that NGx will threaten individual autonomy in daily food choice. The majority of researchers do not think that NGx will lead to discrimination against and/or stigmatization of people who do not comply with NGx dietary recommendations. Despite this optimism among NGx researchers, we suggest that key risk factors raised by the socioethical context in which NGx applications will be implemented need to be considered.
  • PublicationAccès libre
    Social support, but not perceived food environment, is associated with diet quality in French-speaking Canadians from the PREDISE study
    (M D P I AG, 2019-12-12) Carbonneau, Élise; Bélanger, Mathieu; Couillard, Charles; Corneau, Louise; Lamarche, Benoît; Lemieux, Simone; Vohl, Marie-Claude; Bouchard, Luigi; Robitaille, Julie; Pelletier, Luc G.; Desroches, Sophie; Houle, Julie; Bégin, Catherine; Langlois, Marie-France; Provencher, Véronique
    The objectives were to assess whether social support for healthy eating and perceived food environment are associated with diet quality, and to investigate if sociodemographic characteristics moderate these associations. A probability sample of French-speaking adults from the Province of Québec, Canada, was recruited in the context of the PREDISE study. Participants reported their perceptions of supportive and non-supportive actions related to healthy eating from close others at home and outside of home (n = 952), and of the accessibility to healthy foods (n = 1035). The Canadian Healthy Eating Index (C-HEI) was calculated based on three Web-based 24 h food recalls. Multiple linear regression models showed that supportive (B = 1.50 (95% CI 0.46, 2.54)) and non-supportive (B = −3.06 (95% CI −4.94, −1.18)) actions related to healthy eating from close others at home were positively and negatively associated with C-HEI, respectively, whereas actions from close others outside of home were not. The negative association between non-supportive actions occurring at home and C-HEI was stronger among participants with lower (vs. higher) levels of education (p interaction = 0.03). Perceived accessibility to healthy foods was not associated with C-HEI (p > 0.05). These results suggest that the social environment may have a stronger influence on healthy eating than the perceived physical environment. This adds support for healthy eating promotion programs involving entire families, especially for more socioeconomically disadvantaged individuals, whose efforts to eat healthily may be more easily thwarted by non-supportive households
  • PublicationAccès libre
    Validity and reliability of self-reported measures of foods and nutrients in pregnancy : a systematic review
    (Springer, 2014-07-17) Vézina-Im, Lydi-Anne; Robitaille, Julie
    This systematic review aims to critically appraise evidence on validity and reliability of self-reported measures of foods and nutrients in pregnancy. PubMed and EMBASE were investigated. Fifty-four studies were included. Food-frequency questionnaires had acceptable evidence of validity when compared with biomarkers (͞r between 0.04 and 0.58; k=19), 24-hour recalls (͞r between 0.12 and 0.63; k=11) and food records: (͞r between 0.28 and 0.65; k=12). Dietary history (͞r between 0.07 and 0.47; k=7) and food records (͞r between 0.25 and 0.53; k=7) had acceptable evidence of validity when compared with biomarkers. 24-hour recalls had poor evidence of validity against biomarkers. Evidence on reliability was good for food-frequency questionnaires, acceptable for the dietary history and inconclusive for 24-hour recalls. The results suggest that food-frequency questionnaires and food records have the strongest evidence of validity when assessing nutrition during pregnancy and more studies are needed to validate 24-hour recalls and the dietary history.
  • PublicationAccès libre
    Influence des effets d'interactions gène-diète sur le profil de risque cardiovasculaire
    (2006) Robitaille, Julie; Lemieux, Simone; Vohl, Marie-Claude
    La maladie cardiovasculaire (MCV) constitue la première cause de mortalité au Canada. Une meilleure compréhension des composantes héréditaires et nutritionnelles impliquées et de l'interaction entre ces composantes est nécessaire pour établir des stratégies de prévention et de traitement appropriées. Dans cette thèse, des facteurs génétiques et nutritionnels ainsi que des effets d'interaction gène-diète influençant le profil de risque cardiovasculaire ont été identifiés. Une intervention nutritionnelle a démontré une amélioration du profil lipidique de femmes suite à une supplémentation en son d'avoine. Dans une étude transversale, les variations génétiques -115G>A, -840OA et -1830T>C du gène codant pour le Récepteur hépatique nucléaire X (LXRa) étaient associées à des concentrations élevées de cholestérol total et modulaient la relation controversée entre l'apport en cholestérol et le profil lipidique. Des gènes candidats du métabolisme des acides gras (les facteurs de transcription PPARoc, PPARS, la protéine de liaison des acides gras (LFABP) et l'enzyme limitante de la (3-oxydation des acides gras (CPT1)) ont été étudiés pour vérifier leur association avec le profil de risque cardiovasculaire et les effets d'interaction avec l'apport en gras. Lorsque l'apport en gras n'était pas considéré, le polymorphisme LFABP T94A n'était pas associé au profil de risque de la MCV. Par contre, le polymorphisme LFABP T94A ainsi que l'interaction entre le polymorphisme et l'apport en matières grasses expliquaient un pourcentage significatif de la variance observée dans les concentrations plasmatiques d'apolipoprotéine B. Des variations génétiques contenues dans les gènes PPARoc, PPARS et CPT1 étaient associées à plusieurs facteurs de risque de la MCV et l'apport alimentaire en gras interagissait avec ces variations génétiques pour moduler des caractéristiques du syndrome métabolique. Cependant, l'obésité viscérale et ses complications métaboliques n'étaient pas modulées par des variations génétiques du gène codant pour une enzyme du métabolisme des glucocorticoïdes, la lip-HSDl. Finalement, le profil de risque cardiovasculaire était modulé par plusieurs effets d'interaction entre l'apport en gras et des gènes de différentes voies métaboliques de facteurs de risque de la MCV. Ces résultats devront être confirmés dans d'autres études mais suggèrent que des effets d'interaction gène-diète modulent le profil de risquecardiovasculaire.
  • PublicationAccès libre
    Validation of an automated self-administered 24-hour dietary recall web application against urinary recovery biomarkers in a sample of French-speaking adults of the province of Québec, Canada
    (Canadian Science Publishing, 2022-01-20) Paradis, Frédérique; Lamarche, Benoît; Robitaille, Julie; Couillard, Charles; Lafrenière, Jacynthe; Tremblay, André; Corneau, Louise; Lemieux, Simone
    The objective of this study was to validate an automated self-administered 24-hour dietary recall web application (R24W) against recovery biomarkers for sodium, potassium and protein intakes and to identify individual characteristics associated with misreporting in a sample of sixty-one men and sixty-nine women aged 20-65 years from Quebec City, Canada. Each participant completed three dietary recalls using the R24W, provided two 24-hour urinary samples and completed questionnaires to document psychosocial factors. Mean reported intakes were 2.2%, 2.1% and 5.0% lower than the urinary reference values respectively for sodium, potassium and proteins (significant difference for proteins only (p=0.04)). Deattenuated correlations between the self-reported intake and biomarkers were significant for sodium (r: 0.48), potassium (r: 0.56) and proteins (r: 0.68). Cross-classification showed that 39.7% (sodium), 42.9% (potassium) and 42.1 % (proteins) of participants were ranked into the same quartile with both methods and only 4.8% (sodium), 3.2% (potassium) and 0.8% (proteins) were ranked in opposite quartiles. Lower body esteem related to appearance was associated with sodium underreporting in women (r: 0.33, p=0.006). No other individual factor was found to be associated with misreporting. These results suggest that the R24W has a good validity for the assessment of sodium, potassium and protein intakes in a sample of French-speaking adults.
  • PublicationRestreint
    Genes, fat intake and cardiovascular disease risk factors in the Quebec Family Study
    (Wiley, 2012-09-06) Bouchard, Claude; Pérusse, Louis; Vohl, Marie-Claude; Robitaille, Julie
    Objective : The aim of this study was to assess gene‐diet interaction effects on cardiovascular disease (CVD) risk factors (waist circumference, plasma triacylglycerol, high‐density lipoprotein‐cholesterol and fasting glucose concentrations, and diastolic and systolic blood pressure) in the Quebec Family Study cohort. Design : Sixty‐four polymorphisms from 45 candidate genes were studied in 645 subjects. Dietary fat intake was obtained from a 3‐day weighted food record. Results : We observed 18 significant interactions at a p value ≤ 0.01. Among them, the Pro12Ala polymorphism in peroxisome proliferator‐activated receptor γ, alone or in interaction with fat intake, significantly modulated waist circumference (p = 0.0005 for both effects). Additionally, the apolipoprotein E genotype in interaction with fat intake was significantly associated with diastolic and systolic blood pressure (p = 0.01 and p = 0.001, respectively). The ghrelin Leu72Met polymorphism also interacted with dietary fat in its relation to waist circumference and triacylglycerol concentrations (p = 0.0004 and p = 0.005). Discussion : These results suggest that several alleles at candidate genes interact with dietary fat intake to modulate well‐known CVD risk factors. The identification of gene‐diet interaction effects is likely to provide useful information concerning the etiology of CVD.