Personne : Humphries, Brittany
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Humphries
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Brittany
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CHU de Québec, Université Laval
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ncf11909457
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Publication Accès libre Health utilities index mark 3 scores for major chronic conditions : population norms for Canada based on the 2013-2014 Canadian Community Health Survey(Statistics Canada, 2018-11-21) Guertin, Jason Robert; Humphries, Brittany; Feeny, David; Tarride, Jean-EricBackground: Utility scores are frequently used as preference weights when estimating quality-adjusted life-years within cost-utility analyses or health-adjusted life expectancies. Though previous Canadian estimates for specific chronic conditions have been produced, these may no longer reflect current patient populations. Data and methods: Data from the 2013-2014 Canadian Community Health Survey were used to provide Canadian utility score norms for seventeen chronic conditions. Utility scores were estimated using the Health Utilities Index Mark 3 (HUI3) instrument and were reported as weighted average (95% confidence intervals [95% CI]) values. In addition to age and sex-stratified analyses, results were also stratified according to the number of reported chronic conditions (i.e., “none” to “≥5”). All results were weighted using sampling and bootstrapped weights provided by Statistics Canada. Results: Utility scores were estimated for 123,654 (97.2%) respondents (weighted frequency = 29,337,370 [97.7%]). Of the chronic conditions that were examined, “Asthma” had the least detrimental effect (weighted average utility score = 0.803 [95%CI 0.795 – 0.811]) on respondents’ utility scores and “Alzheimer’s disease or any other dementia” had the worst (weighted average utility score = 0.374 [95%CI 0.323 – 0.426]). Respondents who reported suffering from no chronic conditions had, on average, the highest utility scores (weighted average utility score = 0.928 [95%CI 0.926 – 0.930]); estimates dropped as a function of the number of reported chronic conditions. Interpretation: Utility score differed between various chronic conditions and as a function of the number of reported chronic conditions. Results also highlight several differences with previously published Canadian utility norms.Publication Accès libre Pertes de salaire occasionnées par le cancer du sein non-métastatique aux conjoints des patientes(2017) Humphries, Brittany; Maunsell, Elizabeth; Lauzier, SophieObjectif: L’objectif de ce mémoire est d’évaluer les pertes de salaire occasionnées aux conjoints des femmes atteintes d’un cancer du sein non-métastatique et ce, au cours des six mois suivant le début du premier traitement à visée curative. Méthodologie: Ce mémoire s’inscrit dans l’étude « Coûts du cancer du sein pour la patiente et sa famille : ampleur, déterminants et relation avec la qualité de vie » incluant 829 femmes ayant eu un cancer du sein non-métastatique recrutées dans huit hôpitaux du Québec ainsi que 427 de leurs proches. Pour répondre à l’objectif de ce mémoire, nous avons retenu les proches étant les conjoints des femmes et ayant un emploi au diagnostic. Les informations pour le calcul des pertes de salaire des conjoints (salaire habituel, durée des absences, compensations reçues) ont été recueillies à partir d’entrevues téléphoniques réalisées avec les conjoints 1 et 6 mois après le début du premier traitement à visée curative de la femme. Résultats: Parmi les 279 conjoints ayant un emploi au moment du diagnostic, 219 (78,5%) ont eu au moins une absence du travail ou ont diminué leurs heures habituellement travaillées en raison du cancer du sein. En moyenne, les conjoints ont été compensés à 66,3% de leur salaire pendant ces absences et périodes de diminution d’heures (écart-type = 43,5%; médiane = 100%). En tentant compte de ces compensations, la valeur médiane des pertes de salaire durant les six mois suivant le diagnostic était de 0$ CAN 2003 (moyenne = 1 819$; écart-type = 5 247$). Conclusion: Les absences du travail touchent la plupart des conjoints des femmes atteintes d’un cancer du sein non-métastatique. Cependant, les pertes de salaire demeurent modestes pour la majorité d’entre eux en raison des compensations reçues.Publication Accès libre Women's beliefs on early adherence to adjuvant endocrine therapy for breast cancer : a theory-based qualitative study to guide the development of community pharmacist interventions(MDPI, 2018-06-09) Guillaumie, Laurence; Provencher, Louise; Humphries, Brittany; Lemieux, Julie.; Lauzier, Sophie; Moisan, Jocelyne; Dionne, Anne; Collins, StéphanieAdjuvant endocrine therapy (AET) taken for a minimum of five years reduces the recurrence and mortality risks among women with hormone-sensitive breast cancer. However, adherence to AET is suboptimal. To guide the development of theory-based interventions to enhance AET adherence, we conducted a study to explore beliefs regarding early adherence to AET. This qualitative study was guided by the Theory of Planned Behavior (TPB). We conducted focus groups and individual interviews among women prescribed AET in the last two years (n = 43). The topic guide explored attitudinal (perceived advantages and disadvantages), normative (perception of approval or disapproval), and control beliefs (barriers and facilitating factors) towards adhering to AET. Thematic analysis was conducted. Most women had a positive attitude towards AET regardless of their medication-taking behavior. The principal perceived advantage was protection against a recurrence while the principal inconvenience was side effects. Almost everyone approved of the woman taking her medication. The women mentioned facilitating factors to encourage medication-taking behaviors and cope with side effects. For adherent women, having trouble establishing a routine was their main barrier to taking medication. For non-adherent women, it was side effects affecting their quality of life. These findings could inform the development of community pharmacy-based adherence interventions.