Logo Université LavalLogo Université Laval
Bibliothèque
Pour savoir comment effectuer et gérer un dépôt de document, consultez le « Guide abrégé – Dépôt de documents » sur le site Web de la Bibliothèque. Pour toute question, écrivez à corpus@ulaval.ca.
 

Personne :
Powell-Davies, Henry

Photo de profil

Adresse électronique

Date de naissance

Projets de recherche

Structures organisationnelles

Fonction

Nom de famille

Powell-Davies

Prénom

Henry

Affiliation

Chaire de recherche du Canada en catalyse verte et procédés sans métaux, Université Laval

ISNI

ORCID

0000-0002-4665-5745

Identifiant Canadiana

ncf11922591

person.page.name

Filtres

20191
Réinitialiser les filtres

Paramètres

Résultats de recherche

Voici les éléments 1 - 1 sur 1
  • PublicationAccès libre
    Revisiting the reduction of indoles by hydrobranes : a combined experimental and computational study
    (ScienceDirect, 2019-02-27) Powell-Davies, Henry; Fontaine, Frédéric-Georges; Jayaraman, Arumugam
    A combined experimental and density functional computational study was used to probe the mechanism for the reduction of indoles using simple borane BH₃·DMS (DMS = dimethyl sulfide). Experimental and computational studies all steer to the formation of the reduced species 1-BH₂-indolines as the resting state for this reaction, as opposed to the historically presumed formation of the unreduced 1-BH₂-indoles, before the addition of a proton source to form the final product indolines. Furthermore, it was observed that molecular H₂ was generated and consumed in the reaction. Computations put forward hydroboration followed by protodeborylation as the very reasonable mechanistic route for the formation of experimentally observed major intermediate 1-BH₂ indolines. For the H₂ consumption in the reaction, computations suggest the frustrated Lewis pair-type heterolytic splitting of H₂ by a bis(3-indolinyl)borane intermediate.