Accuracy of Doppler-echocardiographic parameters for the detection of aortic bileaflet mechanical prothetic valve dysfunction

Authors: Smadi, Othman; Garcia, Julio; Pibarot, Philippe; Gaillard, Emmanuel; Hassan, Ibrahim; Kadem, Lyes
Abstract: Aims : In vitro and in vivo studies were performed to evaluate the diagnostic accuracy of the different Doppler-echocardiographic parameters proposed in the American Society of Echocardiography guidelines to identify dysfunction of bileaflet mechanical valves (BMV) in the aortic position. Methods and results : Two models of BMV (St Jude HP, MCRI On-X) of different sizes (21;23;25;27 mm) were tested in vitro under a wide range of cardiac outputs (3–7 L/min). The motion of one or both leaflets was restricted to induce a mild (25% restriction in total valve orifice area) and moderate-to-severe (50% restriction in total valve area). Doppler-echocardiographic parameters of valve function were also measured in 17 patients with BMV of whom 4 had valve dysfunction confirmed by cinefluoroscopy. The specificity of all the parameters was high (in vitro: 83–100%; in vivo: 69–100%), but the sensitivity was low (range: 0–83% and 25–100%, respectively). A higher cut-off value for the ratio of peak left ventricular outflow tract velocity to peak aortic velocity or Doppler velocity index (DVI) (<0.35 instead of 0.3 or 0.25) improved the sensitivity (>90%) for the detection of moderate-to-severe dysfunction but remained low for mild dysfunction (50%). Furthermore, a difference of normal reference effective orifice area (EOA) minus measured EOA (EOA-D) >1 standard deviation identified mild and moderate-to-severe dysfunction with sensitivity of 61 and 100%, respectively. Conclusion : The Doppler-echocardiographic parameters and criteria proposed in the guidelines lack sensitivity for the detection of BMV dysfunction. The utilization of a DVI < 0.35 or an EOA-D > 1 SD improved the sensitivity (>90%) for the detection of moderate-to-severe dysfunction, but the sensitivity remained suboptimal (<65%) for detection of mild dysfunction.
Document Type: Article de recherche
Issue Date: 1 February 2014
Open Access Date: Restricted access
Document version: VoR
Permalink: http://hdl.handle.net/20.500.11794/7350
This document was published in: European Heart Journal. Cardiovascular Imaging, Vol. 15 (2), 142–151 (2014)
https://doi.org/10.1093/ehjci/jet059
Oxford University Press
Alternative version: 10.1093/ehjci/jet059
23677918
Collection:Articles publiés dans des revues avec comité de lecture

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