Prosthesis–patient mismatch and clinical outcomes : the evidence continues to accumulate

Authors: Dumesnil, Jean G.Pibarot, Philippe
Abstract: In this issue of the Journal, Ruel and associates1 report that aortic valve prosthesis–patient mismatch (PPM) predominantly affects patients with left ventricular (LV) dysfunction. As they point out, PPM remains a controversial issue. On the one hand, there is indeed an increasing body of evidence suggesting that PPM occurs frequently and has important clinical consequences. To the opposite, some authors have argued that PPM is a rare phenomenon without relevant clinical implications. The article from Ruel and colleagues brings new evidence from two standpoints: (1) It further documents the impact of PPM on long-term clinical outcomes such as survival, freedom from heart failure, and LV mass regression, whereas there has been a paucity of data in this regard and most studies have been limited to the short or medium term; (2) it adds a new dimension to this type of study in that it examines whether PPM and preoperative LV function interact with regard to their impact on these outcomes.
Document Type: Article de recherche
Issue Date: 1 May 2006
Open Access Date: Restricted access
Document version: VoR
Permalink: http://hdl.handle.net/20.500.11794/4788
This document was published in: Journal of thoracic and cardiovascular surgery, Vol. 131 (5), 952–955 (2006)
http://dx.doi.org/10.1016/j.jtcvs.2005.12.032
Elsevier
Alternative version: 10.1016/j.jtcvs.2005.12.032
http://www.ncbi.nlm.nih.gov/pubmed/16678574
Collection:Articles publiés dans des revues avec comité de lecture

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