Highly enantioselective iron(II)-catalyzed opening reaction of aromatic meso-epoxides with indoles

Authors: Plancq, Baptiste; Lafantaisie, Mathieu; Companys, Simon; Maroun, Cendrella; Ollevier, Thierry
Abstract: A highly enantioselective method for the catalytic cis-stilbene oxide opening reaction with indole derivatives was developed. The scope of the reaction was studied with a selection of aromatic meso-epoxides and various indoles, and the desired 2-(indol-3-yl)ethanol derivatives were obtained in good to excellent yields with excellent enantioselectivities (from 96 to >99% ee).
Document Type: Article de recherche
Issue Date: 26 September 2013
Open Access Date: 16 March 2016
Document version: AM
Permalink: http://hdl.handle.net/20.500.11794/369
This document was published in: Organic and biomolecular chemistry, Vol. 11 (43), 7463–7466 (2013)
https://doi.org/10.1039/c3ob41782d
Royal Society of Chemistry
Alternative version: 10.1039/c3ob41782d
24091700
Collection:Articles publiés dans des revues avec comité de lecture

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