Farming practices and the respiratory health risks of swine confinement buildings

Authors: Cormier, YvonIsraël-Assayag, EvelyneRacine-Bédard, GaétaneDuchaine, Caroline
Abstract: This study investigated whether clean swine confinement buildings (SCB) are less harmful to the respiratory system than older and dirtier facilities. Eight healthy volunteers were exposed for 4 h, at 1 week intervals, to eight SCB representing the widest possible range of cleanliness. Each volunteer and a technician rated the SCB for cleanliness from 1±10, 1 being the cleanest possible. Airborne dust, bacteria, endotoxin levels, molds, and ammonia were measured. For each volunteer measured, before and after each exposure, forced expiratory flows (forced expiratory volume in one second (FEV1), and forced vital capacity), white cells in nasal wash and venous blood, and nasal lavage levels of interleukin (IL)-8 and serum levels of IL-6. A methacholine challenge was obtained at baseline and following each exposure. Cleanliness scores ranged 1.5±8.25. Mean airborne levels were: dust 3.54 mg.m-3 bacteria 4.256105 CFU.m-3; endotoxins 404 EU.m-3; molds 883 CFU.m-3; ammonia 20.7 parts per million (ppm). Expiratory flows decreased after exposure (FEV1 from 4.8 0.7 to 4.4 0.7, p<0.001), neutrophils in the nasal wash and white blood cells increased (28.5 37 to 424 2076103 , 5.4 1.0 to 7.4 1.76109 cells.mL-1 respectively), IL-8 increased from 158 311 to 2679 639 pg.mL-1, IL-6 from 0.15 0.26 to 2.34 0.92 pg.mL-1, (p<0.001). All SCB were similarly harmful. In conclusion, modern farming has not succeeded in making swine confinement buildings inoffensive to exposed subjects.
Document Type: Article de recherche
Issue Date: 1 March 2000
Open Access Date: Restricted access
Document version: VoR
Permalink: http://hdl.handle.net/20.500.11794/12894
This document was published in: European Respiratory Journal, Vol. 15 (3), 560–565 (2000)
https://doi.org/10.1034/j.1399-3003.2000.15.22.x
European Respiratory Society
Alternative version: 10.1034/j.1399-3003.2000.15.22.x
10759453
Collection:Articles publiés dans des revues avec comité de lecture

Files in this item:
SizeFormat 
porcheries santé 2000ERJ.pdf
202.01 kBAdobe PDF    Request a copy
All documents in CorpusUL are protected by Copyright Act of Canada.